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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IKBKE
All Species:
10.3
Human Site:
S469
Identified Species:
20.61
UniProt:
Q14164
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14164
NP_054721.1
716
80462
S469
R
T
S
L
L
Y
L
S
S
S
L
G
T
E
R
Chimpanzee
Pan troglodytes
XP_001146274
752
83533
E406
Q
E
L
K
A
A
A
E
L
R
S
R
L
R
T
Rhesus Macaque
Macaca mulatta
XP_001088252
716
80390
S469
R
T
S
L
L
Y
L
S
S
S
L
G
T
E
R
Dog
Lupus familis
XP_536108
791
89060
S518
R
M
A
L
L
F
L
S
S
S
L
G
T
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0T8
717
80921
G471
R
T
A
L
L
Y
L
G
S
S
L
G
T
E
R
Rat
Rattus norvegicus
Q9QY78
757
86848
L459
R
A
A
M
M
N
L
L
R
N
N
S
C
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508346
1039
114867
H473
M
A
L
L
F
L
N
H
S
G
Q
G
Q
D
R
Chicken
Gallus gallus
Q5ZJB4
759
86125
A464
R
L
F
Q
G
Q
R
A
A
M
L
S
L
L
R
Frog
Xenopus laevis
Q6DFJ6
725
83252
T474
K
L
N
F
C
N
R
T
T
E
K
D
L
K
I
Zebra Danio
Brachydanio rerio
Q4G3H4
758
87129
Q498
D
L
E
K
Y
S
D
Q
M
Q
Y
G
I
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEZ5
751
86354
E497
T
K
E
Q
A
R
Y
E
M
L
V
S
G
I
N
Honey Bee
Apis mellifera
XP_396937
720
81974
E464
T
E
L
T
R
L
L
E
K
C
Q
H
S
K
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.8
97.3
79.9
N.A.
82.5
20.7
N.A.
50.6
21.7
47.8
21.5
N.A.
23.1
37.3
N.A.
N.A.
Protein Similarity:
100
55
98.8
83.5
N.A.
91
39.6
N.A.
58.9
40.7
64.2
39.7
N.A.
38.4
56.6
N.A.
N.A.
P-Site Identity:
100
0
100
80
N.A.
86.6
13.3
N.A.
26.6
20
0
6.6
N.A.
0
6.6
N.A.
N.A.
P-Site Similarity:
100
6.6
100
93.3
N.A.
93.3
40
N.A.
33.3
33.3
33.3
6.6
N.A.
6.6
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
25
0
17
9
9
9
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
9
0
0
9
0
0
% C
% Asp:
9
0
0
0
0
0
9
0
0
0
0
9
0
9
0
% D
% Glu:
0
17
17
0
0
0
0
25
0
9
0
0
0
34
9
% E
% Phe:
0
0
9
9
9
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
0
9
0
50
9
0
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
9
% I
% Lys:
9
9
0
17
0
0
0
0
9
0
9
0
0
17
0
% K
% Leu:
0
25
25
42
34
17
50
9
9
9
42
0
25
17
0
% L
% Met:
9
9
0
9
9
0
0
0
17
9
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
17
9
0
0
9
9
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
9
0
0
17
0
9
0
9
0
9
17
0
9
0
0
% Q
% Arg:
50
0
0
0
9
9
17
0
9
9
0
9
0
9
50
% R
% Ser:
0
0
17
0
0
9
0
25
42
34
9
25
9
9
17
% S
% Thr:
17
25
0
9
0
0
0
9
9
0
0
0
34
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
25
9
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _